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If you have too little B12 in your body, your nails might turn brown-gray or bluish

However, many of the studies are small and have methodological flaws, which makes it difficult to give firm guidance on this supplement or confirm its effects

Factors with a p -value less than or equal to 0.25 in bivariate analysis were considered candidates for multivariate modeling

The product is supplied as a lyophilised powder in sealed pharmaceutical-grade vials, labelled with lot number, fill weight and synthesis date

Therefore, cortical GABA has a beneficial rather than a detrimental role in PD, and GABA reduction may donate to increased motor symptom expression (van Nuland et al

At the same time 32% of those studied experienced adverse events, including liver dysfunction and one case of anaphylaxis (Alzahrani et al., Cureus 2025, PMID 40013212)